Oracle Database Discussions

Hi All,
I tried installing oracle10g-10.1.0 on Fedora core 2.My installation was successful.But i'm not able to start sqlplus after my installation.I have made the necessary changes in the .bash_profile.Please do find the contents of the file and let me know what i need to do further for me to start both my sqlplus and isqlplus.when i go to the bin directory and execute sqlplus as oracle user i get the following error messages.
Error 6 initializing SQL*Plus
Message file sp1<lang>.msb not found
SP2-0750: You may need to set ORACLE_HOME to your Oracle software directory.
How can i solve this error.Your suggestions are greatly appreciated.The contents of my .bash_profile are as follows.Pls advice on the same.Thanks in advance.
# .bash_profile

# Get the aliases and functions
if [ -f ~/.bashrc ]; then
. ~/.bashrc
fi

# User specific environment and startup programs
umask 022

PATH=$PATH:$HOME/bin

unset USERNAME
export ORACLE_BASE=/u01/app/oracle
export ORACLE_HOME=$ORACLE_BASE/product/10.1.0/Db_1
export ORACLE_SID=orcl
export PATH=$PATH:$ORACLE_HOME/bin
export PATH
export LD_LIBRARY_PATH=$ORACLE_HOME/lib

#/u01/app/oracle/product/10.1.0/db_1/bin

#NLS_LANG=american_america.US7ASCII
#export NLS_LANG

#ORA_NLS33=$ORACLE_HOME/ocommon/nls/admin/data
#export ORA_NLS33

Thanks,
Rama